Bioidentical Hormone Replacement Therapy
Restore Balance, Feel Like Yourself Again
Bioidentical Hormone Replacement Therapy (BHRT) is a personalized, medically supervised approach to restoring hormonal balance using hormones that are structurally identical to those naturally produced by the human body. Unlike conventional hormone replacement therapies, which often use synthetic or animal-derived hormones, BHRT relies on bioidentical molecules typically derived from plant sources such as soy or yams. These hormones are precisely compounded to match your unique physiological needs—offering relief from symptoms associated with hormone decline while promoting optimal health and wellness.
BHRT gained significant momentum in the years following the 2002 Women’s Health Initiative (WHI) study, which raised concerns about the risks associated with traditional hormone therapy. Although later analyses clarified much of the initial fear, many patients sought safer, more individualized alternatives. Bioidentical hormones emerged as a more natural solution, aiming to replicate the body’s natural hormone rhythms while reducing unwanted side effects.
One of the most trusted and widely used BHRT systems today is Biote, a comprehensive platform that provides both topical creams and hormone pellets. Biote creams offer a non-invasive method for hormone delivery and can be tailored to exact dosages based on lab values. Meanwhile, Biote’s subcutaneous hormone pellets provide a steady, consistent release of hormones such as estrogen or testosterone over a period of three to six months. These tiny pellets, inserted just beneath the skin in a simple in-office procedure, eliminate the hormonal fluctuations often seen with pills or injections and require no daily maintenance—making them a convenient, long-term option for many patients.
The benefits of BHRT are well-documented and increasingly supported by clinical research. In women, BHRT can significantly reduce symptoms of menopause such as hot flashes, mood swings, night sweats, vaginal dryness, insomnia, and decreased libido. In men, testosterone-based BHRT has been shown to improve muscle mass, energy levels, mental clarity, and sexual function. Both men and women may also experience enhanced cognitive function, better sleep quality, improved skin tone, and increased emotional well-being. Additionally, bioidentical hormones have demonstrated protective effects on bone density and cardiovascular health when prescribed responsibly.
Multiple studies have confirmed that BHRT is both effective and well-tolerated when managed under medical supervision. For example, research published in Maturitas and The Journal of Clinical Endocrinology & Metabolism has shown that transdermal estradiol and bioidentical progesterone provide symptom relief with a lower risk profile compared to synthetic hormone combinations. In men, physiological testosterone replacement has been linked to improvements in insulin sensitivity and lipid metabolism, which can reduce the risks associated with metabolic syndrome.
Despite its success, BHRT—particularly pellet therapy—has faced its share of stigma over the years. Critics have questioned its regulation, safety, and scientific legitimacy. However, much of this skepticism stems from outdated data or confusion between compounded and unregulated hormone products. It’s important to understand that reputable systems like Biote work exclusively with FDA-registered 503A and 503B compounding pharmacies, adhere to strict quality standards, and rely on comprehensive lab testing to guide treatment. Additionally, bioidentical hormones differ structurally and functionally from synthetic alternatives, which is why many patients report a more natural and balanced response.
At Onyxx, we believe that hormone health is foundational to overall wellness. Our providers are Biote-certified and extensively trained to evaluate your symptoms, order the appropriate lab work, and design a customized BHRT plan that suits your lifestyle and goals. Whether you are dealing with perimenopause, menopause, andropause, adrenal fatigue, or simply a general sense of imbalance, we are here to help you reclaim your vitality through science-based, personalized care.
If you are ready to take the next step toward hormonal balance, energy restoration, and renewed well-being, we invite you to schedule a consultation. Together, we’ll explore if BHRT with Biote creams or pellets is the right solution for you.